Invitrogen™ Noto Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5143403

Catalog No. PIPA5143403

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial.

Transcription regulator acting downstream of both FOXA2 and T during notochord development. Required for node morphogenesis. Is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning; acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. Plays a role in regulating axial versus paraxial cell fate.

Specifications

• Antigen: Noto
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Noto
• Gene Alias: Flh; floating head homolog; homeobox protein notochord; MmNot; Not; Not homeodomain protein; NOTO; notochord homeobox; notochord homolog; notochord homolog (Xenopus laevis); tc; truncate
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 30260
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed)
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: 0
• Gene Symbols: Noto
• Immunogen: Recombinant protein encompassing a sequence within the center region of zebrafish Flh. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Zebrafish
• Product Type: Antibody
• Isotype: IgG