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Invitrogen™ NOV Polyclonal Antibody
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Catalog No. PIPA5110839
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100 μL
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PIPA5110839 100 μL
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Catalog No. PIPA5110839 Supplier Invitrogen™ Supplier No. PA5110839
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LPEPNCPAPR KVEVPGECCE KWICGPDEED SLGGLTLAAY RPEATLGVEV SDSSVNCIEQ TTEWTACSKS CGMGFSTRVT NRNRQCEMLK QTRL Highest antigen sequence indentity to the following orthologs: Mouse - 81%, Rat - 80%.

NOV is a member of the CCN family of secreted, cysteine-rich regulatory proteins. The full-length NOV protein contains four structural domains that confer distinct, and sometimes opposing, biological activities. Elevated expression of NOV is associated with certain tumors, including Wilm's tumor and most nephroblastomas. However, in other tumor types and certain cancer cell lines, increased tumorigenicity and proliferation is correlated with decreased NOV expression. Additionally, NOV induces cell adhesion and cell migration by signaling through specific cell-surface integrins, and by binding to heparin sulfate proteoglycans and to fibulin 1C. NOV has also been reported to exert proangiogenic activities.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NOV
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CCN3
Gene Accession No. P48745
Gene Alias C130088N23Rik; CCN family member 3; CCN3; Cellular communication network factor 3; IBP-9; IGF-binding protein 9; IGFBP9; IGFBP-9; Insulin-like growth factor-binding protein 9; Nephro blastoma-overexpressed gene protein homolog; nephroblastoma overexpressed; nephroblastoma overexpressed gene; nephroblastoma overexpressed gene protein homolog; nephroblastoma-overexpressed gene protein homolog; NOV; NovH; protein NOV homolog
Gene Symbols CCN3
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human NOV. Recombinant protein control fragment (Product #RP-108154).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4856
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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