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Invitrogen™ NOX1 Polyclonal Antibody
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Catalog No. PIPA5103220
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PIPA5103220 100 μL
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Catalog No. PIPA5103220 Supplier Invitrogen™ Supplier No. PA5103220
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total NOX1.

Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Three splice variants of NOX1 have been identified, NOH-1L, NOH-1S and NOH-1Lv. NOH-1S is a voltage-gated proton channel that participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H (+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain. NOX1 have the potential to be effective treatments for a range of ischemic diseases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NOX1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Nox1
Gene Accession No. Q8CIZ9, Q9WV87, Q9Y5S8
Gene Alias GP91 phox homolog; GP91-2; mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating); mitogenic oxidase 1; MOX1; MOX-1; NADH/NADPH mitogenic oxidase subunit P65-MOX; NADPH oxidase 1; NADPH oxidase 1 alpha; NADPH oxidase homolog-1; NOH1; NOH-1; Nox1; NOX-1; NOX1a; NOX1alpha
Gene Symbols Nox1
Host Species Rabbit
Immunogen A synthesized peptide derived from human NOX1(Accession Q9Y5S8), corresponding to amino acid residues R471-H521.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114243, 237038, 27035
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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