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Invitrogen™ NOX1 Polyclonal Antibody
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Catalog No. PIPA579751
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100 μg
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Catalog No. Quantity
PIPA579751 100 μg
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Catalog No. PIPA579751 Supplier Invitrogen™ Supplier No. PA579751
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: HELA whole cell, MCF-7 whole cell. IHC: Human Lung Cancer Tissue.

Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Three splice variants of NOX1 have been identified, NOH-1L, NOH-1S and NOH-1Lv. NOH-1S is a voltage-gated proton channel that participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H (+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain. NOX1 have the potential to be effective treatments for a range of ischemic diseases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NOX1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.01mg sodium azide
Gene Nox1
Gene Accession No. Q9Y5S8
Gene Alias GP91 phox homolog; GP91-2; mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating); mitogenic oxidase 1; MOX1; MOX-1; NADH/NADPH mitogenic oxidase subunit P65-MOX; NADPH oxidase 1; NADPH oxidase 1 alpha; NADPH oxidase homolog-1; NOH1; NOH-1; Nox1; NOX-1; NOX1a; NOX1alpha
Gene Symbols Nox1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence in the middle region of human NOX1 (354-374aa, HIRAAGDWTENLIRAFEQQYS).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27035
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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