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Invitrogen™ NOX1 Polyclonal Antibody
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Catalog No. PIPA588280
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100 μL
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PIPA588280 100 μL
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Catalog No. PIPA588280 Supplier Invitrogen™ Supplier No. PA588280
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: WYKFQCADHN LKTKKIYFYW ICRETGAFSW FNNLLTSLEQ EMEELGKVGF LNYRLFLTGW DSNIVGHAAL NFDKATDIVT GLKQKTSFGR PMWDNEFSTI ATSHPKSVVG VFLCGPRTLA KSLRKCCHRY SSLDPRKVQF YFNKENF Positive Samples: Rat liver; Cellular Location: Cell projection, Multi-pass membrane protein, invadopodium membrane.

Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Three splice variants of NOX1 have been identified, NOH-1L, NOH-1S and NOH-1Lv. NOH-1S is a voltage-gated proton channel that participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H (+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain. NOX1 have the potential to be effective treatments for a range of ischemic diseases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NOX1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.98 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Nox1
Gene Accession No. Q8CIZ9, Q9Y5S8
Gene Alias GP91 phox homolog; GP91-2; mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating); mitogenic oxidase 1; MOX1; MOX-1; NADH/NADPH mitogenic oxidase subunit P65-MOX; NADPH oxidase 1; NADPH oxidase 1 alpha; NADPH oxidase homolog-1; NOH1; NOH-1; Nox1; NOX-1; NOX1a; NOX1alpha
Gene Symbols Nox1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 418-564 of human NOX1 (NP_0089832?).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 237038, 27035
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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