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Invitrogen™ NOX1 Polyclonal Antibody
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Catalog No. PIPA597106
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100 μL
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PIPA597106 100 μL
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Catalog No. PIPA597106 Supplier Invitrogen™ Supplier No. PA597106
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KSIWYKFQCA DHNLKTKKIY FYWICRETGA FSWFNNLLTS LEQEMEELGK VGFLNYRLFL TGWDSNIVGH AALNFDKATD IVTGLKQKTS FGRPMWDNEF STIATSHPKS VVGVFLCGPR TLAKSLRKCC HRYSSLDPRK VQFYFNKENF; Positive Samples: HT-29, A-549, SW480; Cellular Location: Cell projection, Multi-pass membrane protein, invadopodium membrane.

Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Three splice variants of NOX1 have been identified, NOH-1L, NOH-1S and NOH-1Lv. NOH-1S is a voltage-gated proton channel that participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H (+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain. NOX1 have the potential to be effective treatments for a range of ischemic diseases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NOX1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.35 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Nox1
Gene Accession No. Q8CIZ9, Q9WV87, Q9Y5S8
Gene Alias GP91 phox homolog; GP91-2; mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating); mitogenic oxidase 1; MOX1; MOX-1; NADH/NADPH mitogenic oxidase subunit P65-MOX; NADPH oxidase 1; NADPH oxidase 1 alpha; NADPH oxidase homolog-1; NOH1; NOH-1; Nox1; NOX-1; NOX1a; NOX1alpha
Gene Symbols Nox1
Host Species Rabbit
Immunogen Synthetic peptide
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114243, 237038, 27035
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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