NOX1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 177721AP150UL

Catalog No. 50-173-1783

Description

Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Three splice variants of NOX1 have been identified, NOH-1L, NOH-1S and NOH-1Lv. NOH-1S is a voltage-gated proton channel that participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H (+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain. NOX1 have the potential to be effective treatments for a range of ischemic diseases.

Specifications

• Antigen: NOX1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NOX1
• Gene Alias: GP91 2, Mitogenic oxidase 1, MOX 1, MOX1, NADPH oxidase 1, NOH 1, NOH1, NOX 1, NOX1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114243, 237038, 27035
• Content And Storage: -20°C
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.23 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q8CIZ9, Q9WV87, Q9Y5S8
• Gene Symbols: Nox1
• Immunogen: NOX1 Fusion Protein Ag12187
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG