NOX2/gp91phox Rabbit anti-Human, Polyclonal, Bioss
Rabbit Polyclonal Antibody
Manufacturer: Bioss BS3889R
DescriptionMox1 and the glycoprotein gp91-phox are largely related proteins that are essential components of the NADPH oxidase. The superoxide-generating NADPH oxidase complex expresses in phagocytes, neuroepithelial bodies, vascular smooth muscle cells, and endothelial cells. It includes a membrane bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. The p22- and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. Mox1 and gp91 contain identical C-terminal sequence identity, yet possess distinct expression patterns. gp91-phox expresses in eosinophils, neutrophils, monocytes, and B-lymphocytes, whereas Mox1 is predominantly detected in the colon, with low expression in the uterus and prostate.
|Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH|
|AMCBX2; C88302; Cgd; CGD91-phox; CYBB; Cyd; Cytochrome b(558) subunit beta; cytochrome b-245 beta chain; cytochrome b-245 beta polypeptide; Cytochrome b-245 heavy chain; cytochrome b-245, beta polypeptide; Cytochrome b558 subunit beta; endothelial type gp91-phox; GP91 PHOX; GP911; gp91-1; gp91phox; gp91-phox; Heme-binding membrane glycoprotein gp91phox; IMD34; NADPH oxidase 2; Neutrophil cytochrome b 91 kDa polypeptide; NOX2; p22 phagocyte B-cytochrome; p91PHOX; p91-PHOX; Superoxide-generating NADPH oxidase heavy chain subunit|
|KLH conjugated synthetic peptide derived from human NOX2/gp91phox.|
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