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NOX2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501732322 Shop All Proteintech Group Inc Products
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50-173-2322 150 μL
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Catalog No. 50-173-2322 Supplier Proteintech Group Inc Supplier No. 190131AP150UL
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Description

Rabbit Polyclonal Antibody

Mox1 and the glycoprotein gp91-phox are largely related proteins that are essential components of the NADPH oxidase. The superoxide-generating NADPH oxidase complex expresses in phagocytes, neuroepithelial bodies, vascular smooth muscle cells, and endothelial cells. It includes a membranebound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. The p22- and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. Mox1 and gp91 contain identical C-terminal sequence identity, yet possess distinct expression patterns. gp91-phox expresses in eosinophils, neutrophils, monocytes, and B-lymphocytes, whereas Mox1 is predomitly detected in the colon, with low expression in the uterus and prostate.

Specifications

Antigen NOX2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene CYBB
Gene Accession No. P04839, Q61093
Gene Alias CYBB, Cytochrome b 245 heavy chain, NOX2, p91 PHOX
Gene Symbols Cybb
Host Species Rabbit
Immunogen NOX2 Fusion Protein Ag5536
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13058, 1536, 66021
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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