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Nox3/NADPH oxidase 3 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985580
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50-198-5580 100 μL
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Catalog No. 50-198-5580 Supplier Bioss Supplier No. BS3683R
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Description

Rabbit Polyclonal Antibody

The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide. NOX3 is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith. It has been suggested that NOX3 is activated by the Transient Receptor Potential Vanilloid 1 (TRPV1), and this activity causes increased levels of reactive oxygen species in the inner ear, which in turn leads to STAT1-mediated inflammation and hearing loss.

Specifications

Antigen Nox3/NADPH oxidase 3
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene NOX3
Gene Accession No. Q9HBY0
Gene Alias GP91-3; gp91phox homolog 3; head-tilt; het; Mitogenic oxidase 2; MOX2; MOX-2; NADPH oxidase 3; NADPH oxidase catalytic subunit-like 3; NAPDH oxidase 3; nmf250; NOX3; NOX-3
Gene Symbols NOX3
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Nox3/NADPH oxidase 3.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 50508
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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