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Invitrogen™ NOX3 Polyclonal Antibody
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Catalog No. PIPA538036
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100 μg
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Catalog No. Quantity
PIPA538036 100 μg
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Catalog No. PIPA538036 Supplier Invitrogen™ Supplier No. PA538036
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Description

Rabbit Polyclonal Antibody

PA5-38036 detects Nox3 in mouse bone marrow and humanG-CSF mobilized CD34+ cells in immunofluorescence analysis. A recommended positive control is 293 cell lysate. NOX3 is not expected to cross-react with other NOX proteins.

The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide. NOX3 is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith. It has been suggested that NOX3 is activated by the Transient Receptor Potential Vanilloid 1 (TRPV1), and this activity causes increased levels of reactive oxygen species in the inner ear, which in turn leads to STAT1-mediated inflammation and hearing loss.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NOX3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene NOX3
Gene Accession No. Q672J9, Q9HBY0
Gene Alias GP91-3; gp91phox homolog 3; head-tilt; het; Mitogenic oxidase 2; MOX2; MOX-2; NADPH oxidase 3; NADPH oxidase catalytic subunit-like 3; NAPDH oxidase 3; nmf250; Nox3; NOX-3
Gene Symbols NOX3
Host Species Rabbit
Immunogen 15 amino acid peptide near the amino terminus of human NOX3.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 224480, 50508
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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