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NOXA2/p67phox Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
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Catalog No. 501730309 Shop All Proteintech Group Inc Products
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50-173-0309 150 μL
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Catalog No. 50-173-0309 Supplier Proteintech Group Inc Supplier No. 155511AP150UL
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Rabbit Polyclonal Antibody

NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). Defects in NCF2 are a cause of chronic granulomatous disease autosomal recessive cytochrome-b-positive type 2 (CGD2). Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.

Specifications

Antigen NOXA2/p67phox
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.29 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene NCF2
Gene Accession No. A7E3N2, O70145, P19878
Gene Alias NADPH oxidase activator 2, NCF 2, NCF2, Neutrophil cytosol factor 2, neutrophil cytosolic factor 2, NOXA2, P67 PHOX, p67phox
Gene Symbols Ncf2
Host Species Rabbit
Immunogen NOXA2/p67phox Fusion Protein Ag7909
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17970, 364018, 4688
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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