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Invitrogen™ NPAS2 Polyclonal Antibody
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Catalog No. PIPA598824
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100 μg
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Catalog No. Quantity
PIPA598824 100 μg
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Catalog No. PIPA598824 Supplier Invitrogen™ Supplier No. PA598824
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Description

Rabbit Polyclonal Antibody

NPAS2 Polyclonal Antibody for ICC/IF, IHC (P), ELISA

Members of the basic helix-loop-helix-PER-ARNT-SIM (bHLH-PAS) family are transcription factors that contain a bHLH DNA binding domain located amino-terminal to a PAS domain. Neuronal PAS domain protein 2 (NPAS2, also designated PAS 4/MOP4) is a member of the bHLH-PAS family and the PAS superfamily. NPAS2, which maps to chromosome 2p11.2-2q13, is expressed primarily in the neurons during the first week of postnatal development. The pattern of NPAS2 expression temporally matches the development of learning and memory, and spatially matches the frontal association/limbic forebrain pathway. NPAS2 may serve a regulatory role in the development and maintenance of long-term memory, and may be required for the processing of complex sensory information. NPAS2 and MOP3 form a transcriptionally active heterodimer which binds to a CACGTGA-containing DNA element and drives transcription from a linked luciferase reporter gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NPAS2
Applications ELISA, Immunohistochemistry (Paraffin), Immunocytochemistry, Western Blot
Classification Polyclonal
Concentration 2.75 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Npas2
Gene Accession No. Q99743
Gene Alias Basic-helix-loop-helix-PAS protein MOP4; bHLHe9; Class E basic helix-loop-helix protein 9; member of PAS protein 4; member of PAS superfamily 4; MOP4; neuronal PAS domain protein 2; neuronal PAS domain-containing protein 2; Neuronal PAS2; NPAS2; PAS domain-containing protein 4; PASD4
Gene Symbols Npas2
Host Species Rabbit
Immunogen Recombinant Human Neuronal PAS domain-containing protein 2 protein (644-763AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4862
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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