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Invitrogen™ NPDC1 Monoclonal Antibody (16E4)
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Catalog No. 01674060
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100 μg
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Catalog No. Quantity
01-674-060 100 μg
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Catalog No. 01-674-060 Supplier Invitrogen™ Supplier No. MA112777
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Description

Mouse Monoclonal Antibody

A suggested positive control for this product is brain tissue lysate.

The discovery of NPDC-1 (neuronal proliferation, differentiation and control protein 1) was the result of a study of genes that were preferentially expressed in immortalized neural precursor cell lines at the onset of contact inhibition of proliferation and subsequent differentiation. It was further found that transfection of transformed cells with NPDC-1 led to increased doubling times and suppression of many characteristics of transformation. NPDC-1 is differentially expressed in brain and lung and has been shown to interact directly with the transcription factor E2F-1 as well as D-type cyclins and cdk2. NPDC-1 has been identified as a modulator of transcriptiona levents mediated by retinoic acid and the protein level and activity of NPDC-1 have been shown to be regulated by phosphorylation mediated proteasomal degradation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NPDC1
Applications Western Blot
Classification Monoclonal
Clone 16E4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 3mM sodium azide; pH 7.5
Gene NPDC1
Gene Accession No. Q64322, Q9NQX5
Gene Alias AI314472; CAB; CAB-; CAB1; CAB-1; DKFZP586J0523; Neural proliferation differentiation and control protein 1; neural proliferation differentiation control-1 protein; neural proliferation, differentiation and control 1; neural proliferation, differentiation and control gene 1; neural proliferation, differentiation and control, 1; NPDC1; NPDC-1; RP23-47P18.6
Gene Symbols NPDC1
Host Species Mouse
Immunogen Synthetic peptide corresponding to human NPDC-1.
Purification Method Ion-exchange Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18146, 296562, 56654
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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