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Invitrogen™ NPDC1 Polyclonal Antibody
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Catalog No. PIPA5101704
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100 μL
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PIPA5101704 100 μL
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Catalog No. PIPA5101704 Supplier Invitrogen™ Supplier No. PA5101704
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total NPDC1.

The discovery of NPDC-1 (neuronal proliferation, differentiation and control protein 1) was the result of a study of genes that were preferentially expressed in immortalized neural precursor cell lines at the onset of contact inhibition of proliferation and subsequent differentiation. It was further found that transfection of transformed cells with NPDC-1 led to increased doubling times and suppression of many characteristics of transformation. NPDC-1 is differentially expressed in brain and lung and has been shown to interact directly with the transcription factor E2F-1 as well as D-type cyclins and cdk2. NPDC-1 has been identified as a modulator of transcriptiona levents mediated by retinoic acid and the protein level and activity of NPDC-1 have been shown to be regulated by phosphorylation mediated proteasomal degradation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NPDC1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NPDC1
Gene Accession No. Q64322, Q9NQX5
Gene Alias AI314472; CAB; CAB-; CAB1; CAB-1; DKFZP586J0523; Neural proliferation differentiation and control protein 1; neural proliferation differentiation control-1 protein; neural proliferation, differentiation and control 1; neural proliferation, differentiation and control gene 1; neural proliferation, differentiation and control, 1; NPDC1; NPDC-1; RP23-47P18.6
Gene Symbols NPDC1
Host Species Rabbit
Immunogen A synthesized peptide derived from human NPDC1(Accession Q9NQX5), corresponding to amino acid residues I188-G238.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18146, 296562, 56654
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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