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NPDC1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981779
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50-198-1779 100 μL
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Catalog No. 50-198-1779 Supplier Bioss Supplier No. BS11913R
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Description

Rabbit Polyclonal Antibody

The discovery of NPDC-1 (neuronal proliferation, differentiation and control protein 1) was the result of a study of genes that were preferentially expressed in immortalized neural precursor cell lines at the onset of contact inhibition of proliferation and subsequent differentiation. It was further found that transfection of transformed cells with NPDC-1 led to increased doubling times and suppression of many characteristics of transformation. NPDC-1 is differentially expressed in brain and lung and has been shown to interact directly with the transcription factor E2F-1 as well as D-type cyclins and cdk2. NPDC-1 has been identified as a modulator of transcriptiona levents mediated by retinoic acid and the protein level and activity of NPDC-1 have been shown to be regulated by phosphorylation mediated proteasomal degradation.

Specifications

Antigen NPDC1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene NPDC1
Gene Accession No. Q9NQX5
Gene Alias AI314472; BOS_12253; CAB; CAB-; CAB1; CAB-1; DKFZP586J0523; Neural proliferation differentiation and control protein 1; neural proliferation differentiation control-1 protein; neural proliferation, differentiation and control 1; neural proliferation, differentiation and control gene 1; neural proliferation, differentiation and control, 1; Npdc1; Npdc-1; RP23-47P18.6
Gene Symbols NPDC1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human NPDC1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56654
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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