Invitrogen™ NPHP3 Monoclonal Antibody (3B1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524451

Catalog No. PIMA524451

Description

Peptide Sequence: NQELLSMGRR EAKLDTENKR LRAELQALQK TYQKILREKE SALEAKYQAM ERAATFEHDR DKVKRQFKIF RETKENEIQD LLRAKRELES KLQRLQAQGI.

Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.

Specifications

• Antigen: NPHP3
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q7Z494
• Gene Symbols: NPHP3
• Immunogen: NPHP3 (NP_694972.3, 106 a.a. ~ 205 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA, Western Blot
• Clone: 3B1
• Conjugate: Unconjugated
• Gene: NPHP3
• Gene Alias: 3632410F03Rik; AI550417; C230078J01; CFAP31; cilia and flagella associated protein 31; D330020E01Rik; Kiaa2000; Meckel syndrome, type 7; MKS7; Nephrocystin-3; nephronophthisis 3 (adolescent); NPH3; NPHP3; pcy; RHPD; RHPD1; SLSN3
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 27031
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid