Invitrogen™ NPHP3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552656

Catalog No. PIPA552656

Description

Immunogen sequence: PEFAHSSIDV EGPFANVNRD DWDIAVASLL QVTPLFSHSL WSNTVRCYLI YTDETQPEMD LFLKDYSPKL KRMCETMGYF FHAVYFPIDV ENQYLTVRKW EIEKS Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 89%.

Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.

Specifications

• Antigen: NPHP3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NPHP3
• Gene Alias: 3632410F03Rik; AI550417; C230078J01; CFAP31; cilia and flagella associated protein 31; D330020E01Rik; Kiaa2000; Meckel syndrome, type 7; MKS7; Nephrocystin-3; nephronophthisis 3 (adolescent); NPH3; NPHP3; pcy; RHPD; RHPD1; SLSN3
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27031
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q7Z494
• Gene Symbols: NPHP3
• Immunogen: Recombinant protein corresponding to Human NPHP3. Recombinant protein control fragment (Product #RP-89775).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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