Invitrogen™ NPHP3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597123

Catalog No. PIPA597123

Description

Immunogen sequence: MGTASSLVSP AGGEVIEDTY GAGGGEACEI PVEVKPKARL LRNSFRRGAG AAAGAGPGSL PRGVGAGGLL GASFKSTGSS VPELEYAAAE YERLRKEYEI FRVSKNQELL SMGRREAKLD TENKRLRAEL; Positive Samples: 293T, Mouse liver; Cellular Location: Cell projection, cilium.

Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.

Specifications

• Antigen: NPHP3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NPHP3
• Gene Alias: 3632410F03Rik; AI550417; C230078J01; CFAP31; cilia and flagella associated protein 31; D330020E01Rik; Kiaa2000; Meckel syndrome, type 7; MKS7; Nephrocystin-3; nephronophthisis 3 (adolescent); NPH3; NPHP3; pcy; RHPD; RHPD1; SLSN3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27031, 74025
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.54 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q7TNH6, Q7Z494
• Gene Symbols: NPHP3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human NPHP3 (NP_6949723).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG