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Invitrogen™ NPL Polyclonal Antibody
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Catalog No. PIPA5110039
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100 μL
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PIPA5110039 100 μL
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Catalog No. PIPA5110039 Supplier Invitrogen™ Supplier No. PA5110039
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MAFPKKKLQG LVAATITPMT ENGEINFSVI GQYVDYLVKE QGVKNIFVNG TTGEGLSLSV SERRQVAEEW VTKGKDKLDQ VIIHVGALSL KESQELAQHA AEIGADGIAV IAPFFLKPWT KDILINFLKE VAAAAPALPF YYYHIPALTG VKIRAEELLD GILDKIPTFQ GLKFSDTDLL DFGQCVDQNR QQQFAFLFGV DEQLLSALVM GATGAVGSTY NYLGKKTNQM LEAFEQKDFS LALNYQFCIQ.

Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N- glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NPL
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.37 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene NPL
Gene Accession No. Q66H59, Q9DCJ9
Gene Alias 0610033B02Rik; C112; C1orf13; dihydrodipicolinate synthetase homolog 1; N-acetylneuraminate lyase; N-acetylneuraminate pyruvate lyase; N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase); N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; NAL; NALase; Npl; NPL1; Sialate lyase; sialate-pyruvate lyase; Sialic acid aldolase; sialic acid lyase
Gene Symbols NPL
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human NPL (NP_110396.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 304860, 74091
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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