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Invitrogen™ NPL Polyclonal Antibody
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Catalog No. PIPA5140278
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100 μL
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PIPA5140278 100 μL
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Catalog No. PIPA5140278 Supplier Invitrogen™ Supplier No. PA5140278
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Description

Rabbit Polyclonal Antibody

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: FVNGTTGEGL SLSVSERRQV AEEWVTKGKD KLDQVIIHVG ALSLKESQEL AQHAAEIGAD Highest antigen sequence indentity to the following orthologs: Rat - 90%, Mouse - 88%.

Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N- glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NPL
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NPL
Gene Accession No. Q9BXD5
Gene Alias 0610033B02Rik; C112; C1orf13; dihydrodipicolinate synthetase homolog 1; N-acetylneuraminate lyase; N-acetylneuraminate pyruvate lyase; N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase); N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; NAL; NALase; Npl; NPL1; Sialate lyase; sialate-pyruvate lyase; Sialic acid aldolase; sialic acid lyase
Gene Symbols NPL
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NPL. Recombinant protein control fragment (Product #RP-109500).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80896
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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