NPM1 Mouse anti-Human, Clone: 1042CT5.2.1, Abnova™
Mouse monoclonal antibody raised against human NPM1.
Manufacturer: Abnova Corporation MAB12333
NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF (MIM 600160). NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia (AML; MIM 601626) (Garzon et al., 2008 [PubMed 18308931]).[supplied by OMIM]
|Mouse monoclonal antibody raised against human NPM1.|
|In PBS (0.09% sodium azide)|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Immunohistochemistry (PFA fixed), Western Blot|
|Immunohistochemistry (1:25) Western Blot (1:1000) The optimal working dilution should be determined by the end user.|
|Recombinant His fusion protein corresponding to human NPM1.|
|Protein G purification|
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