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NPR-B Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984654
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50-198-4654 100 μL
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Catalog No. 50-198-4654 Supplier Bioss Supplier No. BS2348R
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Description

Rabbit Polyclonal Antibody

This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide, which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.

Specifications

Antigen NPR-B
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Npr2
Gene Accession No. P20594
Gene Alias AMDM; ANPb; ANP-B; ANPRB; ANPR-B; atrial natriuretic peptide B-type receptor; Atrial natriuretic peptide receptor 2; atrial natriuretic peptide receptor B; Atrial natriuretic peptide receptor type B; cn; ECDM; GC-B; GC-B2; GC-B3; guanylate cyclase 2B; Guanylate cyclase B; guanylyl cyclase-B; GUC2B; GUCY2B; mNPR-B; natriuretic peptide receptor 2; natriuretic peptide receptor B type; natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B); natriuretic peptide receptor-B; Nppb receptor; Npr2; NPRB; NPR-B; NPRBi; pwe; SNSK
Gene Symbols Npr2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human NPR-B.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4882
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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