Invitrogen™ NPR1 Polyclonal Antibody

Catalog No.	Quantity
PA550486	100 μL

Catalog No. PA550486 Supplier Invitrogen™ Supplier No. PA550486

Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total NPR1 protein.

Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms. The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A and type B. Also see NPR3, which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides and BNP, respectively).

Specifications

• Antigen: NPR1
• Applications: Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 1.3 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene: NPR1
• Gene Accession No.: P16066, P18293, P18910
• Gene Alias: AI893888; ANPa; ANP-A; ANPRA; ANPR-A; atrial natriuretic peptide A-type receptor; atrial natriuretic peptide receptor 1; atrial natriuretic peptide receptor A; atrial natriuretic peptide receptor type A; atrionatriuretic peptide receptor A; Gca; GC-A; Guanylate cyclase A; guanylyl cyclase-A; GUC2A; GUCY2A; natriuretic peptide A type receptor; natriuretic peptide receptor 1; natriuretic peptide receptor A; natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A); Nppa receptor; Npr1; Npra; NPR-A; Pndr; testicular tissue protein Li 20
• Gene Symbols: NPR1
• Host Species: Rabbit
• Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human Natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 18160, 24603, 4881
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG