NPR2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 551131AP150UL

Catalog No. 50-173-5992

Description

The antibody is specific to NPR2.

This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide, which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.

Specifications

• Antigen: NPR2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NPR2
• Gene Alias: AMDM, ANP B, ANPR B, ANPRB, GC B, Guanylate cyclase B, GUC2B, GUCY2B, Natriuretic Peptide Receptor B, NPR2, NPRB
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 230103, 4882
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.38 mg/mL
• Formulation: 0.1 M glycine, 0.1 M sodium bicarbonate with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P20594, Q6VVW5
• Gene Symbols: NPR2
• Immunogen: Peptide
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG