NPR2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-5992	150 μL

Catalog No. 50-173-5992 Supplier Proteintech Group Inc Supplier No. 551131AP150UL

Description

Rabbit Polyclonal Antibody

The antibody is specific to NPR2.

This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide, which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.

Specifications

• Antigen: NPR2
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.38 mg/mL
• Conjugate: Unconjugated
• Formulation: 0.1 M glycine, 0.1 M sodium bicarbonate with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: NPR2
• Gene Accession No.: P20594, Q6VVW5
• Gene Alias: AMDM, ANP B, ANPR B, ANPRB, GC B, Guanylate cyclase B, GUC2B, GUCY2B, Natriuretic Peptide Receptor B, NPR2, NPRB
• Gene Symbols: NPR2
• Host Species: Rabbit
• Immunogen: Peptide
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 230103, 4882
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG