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Invitrogen™ Npr2 Recombinant Rabbit Monoclonal Antibody (1S1H1)
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Catalog No. PIMA537887
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100 μL
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PIMA537887 100 μL
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Catalog No. PIMA537887 Supplier Invitrogen™ Supplier No. MA537887
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: Mouse lung, Mouse spleen Immunogen sequence: NLLLRMEQYA NNLEKLVEER TQAYLEEKRK AEALLYQILP HSVAEQLKRG ETVQAEAFDS VTIYFSDIVG FTALSAESTP MQVVTLLNDL YTCFDAIIDN F.

This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide, which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Npr2
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 1S1H1
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Npr2
Gene Accession No. Q6VVW5
Gene Alias AMDM; ANPb; ANP-B; ANPRB; ANPR-B; atrial natriuretic peptide B-type receptor; atrial natriuretic peptide receptor 2; atrial natriuretic peptide receptor B; atrial natriuretic peptide receptor type B; cn; ECDM; GC-B; GC-B2; GC-B3; guanylate cyclase 2B; guanylate cyclase B; guanylyl cyclase-B; GUC2B; GUCY2B; mNPR-B; natriuretic peptide receptor 2; natriuretic peptide receptor B type; natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B); natriuretic peptide receptor-B; Nppb receptor; NPR2; NPRB; NPR-B; NPRBi; pwe; SNSK
Gene Symbols Npr2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 800-900 of human ANPRB/NRP2 (P20594).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 230103
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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