Invitrogen™ NPR3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120508

Catalog No. PIPA5120508

Description

Positive test controls include: NCI-H460, Mouse heart, Mouse lung, Mouse kidney, Rat heart. The target is usually found in the following locations: Membrane, Single-pass type I membrane protein. Immunogen sequence: AALVYSDDKL ERNCYFTLEG VHEVFQEEGL HTSIYSFDET KDLDLEDIVR NIQASERVVI MCASSDTIRS IMLVAHRHGM TSGDYAFFNI ELFNSSSYGD GSWKRGDKHD FEAKQAYSSL QTVTLLRTVK PEFEKFSMEV KSSVEKQGLN MEDYVNMFVE GFHDAILLYV LALHEVLRAG YSKKDGGKII QQTWNRTFEG IAGQVSIDAN GDRYGDFSVI AMTDVEAGTQ EVIGDYFGKE GRFEMRPNVK YPWGPLKLRI DENRIVEHTN SSPCKSSGGL E.

This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: NPR3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NPR3
• Gene Alias: A NPR-C; ANP-C; ANP-CR; ANPRC; ANPR-C; atrial natriuretic peptide clearance receptor; Atrial natriuretic peptide clearence receptor 3; atrial natriuretic peptide C-type receptor; atrial natriuretic peptide receptor 3; atrial natriuretic peptide receptor 3-like; atrial natriuretic peptide receptor type C; atrionatriuretic peptide receptor C; C5orf23; EF-2; guanylate cyclase C; GUCY2B; lgj; longjohn; natriuretic peptide receptor 3; natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C); Nppc receptor; Npr3; NPRC; NPR-C; stri; strigosus
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18162, 25339, 4883
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.19 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P17342, P41740, P70180
• Gene Symbols: NPR3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-480 of human NPR3 (NP_0011913041).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG