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Invitrogen™ NPY Polyclonal Antibody
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Catalog No. PIPA5120859
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100 μL
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PIPA5120859 100 μL
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Catalog No. PIPA5120859 Supplier Invitrogen™ Supplier No. PA5120859
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Description

Rabbit Polyclonal Antibody

Positive test controls include: SH-SY5Y. The target is usually found in the following locations: Secreted. Immunogen sequence: YPSKPDNPGE DAPAEDMARY YSALRHYINL ITRQRYGKRS SPETLISDLL MRESTENVPR TRLEDPAMW.

This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase, regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NPY
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.35 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene NPY
Gene Accession No. P01303, P07808, P57774
Gene Alias 0710005A05Rik; C-flanking peptide of NPY; CPON; involved in appetite regulation; LOC100912228; Neuropeptide tyrosine; Neuropeptide Y; neuropeptide Y precursor; Neuropeptide-Y; Npy; NPY02; OTTHUMP00000201947; prepro-neuropeptide Y; proneuropeptide Y; pro-neuropeptide Y; pro-neuropeptide Y-like; PYY4; RATNPY; RATNPY02
Gene Symbols NPY
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100912228, 109648, 24604, 4852
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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