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Invitrogen™ NPY Polyclonal Antibody
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Catalog No. PIPA519568
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100 μg
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Catalog No. Quantity
PIPA519568 100 μg
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Catalog No. PIPA519568 Supplier Invitrogen™ Supplier No. PA519568
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Description

Rabbit Polyclonal Antibody

Heat mediated antigen retrieval recommended prior to tissue staining. This antibody is predicted to react with sheep, rabbit, chicken, guinea pig, cow, pigeon, pig, zebrafish and rhesus monkey based on sequence homology.

This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase, regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NPY
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.9 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA and 0.02% sodium azide; pH 7.4
Gene NPY
Gene Accession No. P01303
Gene Alias 0710005A05Rik; C-flanking peptide of NPY; CPON; involved in appetite regulation; LOC100912228; Neuropeptide tyrosine; Neuropeptide Y; neuropeptide Y precursor; Neuropeptide-Y; Npy; NPY02; OTTHUMP00000201947; prepro-neuropeptide Y; proneuropeptide Y; pro-neuropeptide Y; pro-neuropeptide Y-like; PYY4; RATNPY; RATNPY02
Gene Symbols NPY
Host Species Rabbit
Immunogen Synthetic peptide conjugated to KLH derived from within residues 1 to the C-terminus of Pig Neuropeptide Y.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4852
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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