Invitrogen™ NPY Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA519568

Catalog No. PIPA519568

Description

Heat mediated antigen retrieval recommended prior to tissue staining. This antibody is predicted to react with sheep, rabbit, chicken, guinea pig, cow, pigeon, pig, zebrafish and rhesus monkey based on sequence homology.

This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase, regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases.

Specifications

• Antigen: NPY
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NPY
• Gene Alias: 0710005A05Rik; C-flanking peptide of NPY; CPON; involved in appetite regulation; LOC100912228; Neuropeptide tyrosine; Neuropeptide Y; neuropeptide Y precursor; Neuropeptide-Y; Npy; NPY02; OTTHUMP00000201947; prepro-neuropeptide Y; proneuropeptide Y; pro-neuropeptide Y; pro-neuropeptide Y-like; PYY4; RATNPY; RATNPY02
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4852
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.9 mg/mL
• Formulation: PBS with 1% BSA and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P01303
• Gene Symbols: NPY
• Immunogen: Synthetic peptide conjugated to KLH derived from within residues 1 to the C-terminus of Pig Neuropeptide Y.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG