Invitrogen™ NQO1 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518022

Catalog No. PIPA518022

Description

This antibody is predicted to react with porcine and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.

NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Altered expression of the protein has been seen in many tumors and is also associated with Alzheimer's disease (AD).

Specifications

• Antigen: NQO1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NQO1
• Gene Alias: AV001255; Azoreductase; DHQU; DIA4; Diaphorase (NADH/NADPH); diaphorase (NADH/NADPH) (cytochrome b-5 reductase); Diaphorase 4; diaphorase 4 (NADH/NADPH); diaphorase-4; dioxin-inducible 1; DTD; DT-diaphorase; menadione reductase; NAD(P)H dehydrogenase (quinone); NAD(P)H dehydrogenase [quinone] 1; NAD(P)H dehydrogenase, quinone 1; NAD(P)H menadione oxidoreductase 1, dioxin inducible; NAD(P)H quinone dehydrogenase 1; NAD(P)H: quinone oxidoreductase 1; NAD(P)H:menadione oxidoreductase; NAD(P)H:menadione oxidoreductase 1; NAD(P)H:Quinone acceptor oxidoreductase type 1; NAD(P)H:quinone oxidoreductase 1; NAD(P)H:quinone oxireductase; NADPH-d; nicotinamide adenine dinucleotide phosphate diaphorase; Nmo1; Nmo-1; Nmor1; NMORI; NQ01; NQO1; Ox1; Ox-1; phylloquinone reductase; QR1; quinone reductase 1
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 1728, 24314
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P05982, P15559
• Gene Symbols: NQO1
• Immunogen: Synthetic peptide sequence (SIPTDNQIKARK) corresponding to the C-terminus amino acids of NQO1 (aa 263-274).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG