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Invitrogen™ NQO1 Polyclonal Antibody
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Catalog No. PIPA582294
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100 μL
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PIPA582294 100 μL
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Catalog No. PIPA582294 Supplier Invitrogen™ Supplier No. PA582294
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: FRSKKAVLSI TTGGSGSMYS LQGIHGDMNV ILWPIQSGIL HFCGFQVLEP QLTYSIGHTP ADARIQILEG WKKRLENIWD ETPLYFAPSS LFDLNFQAGF LMKKEVQDEE KNKKFGLSVG HHLGKSIPTD NQIKAR Highest antigen sequence indentity to the following orthologs: Mouse - 88%, Rat - 85%.

NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Altered expression of the protein has been seen in many tumors and is also associated with Alzheimer's disease (AD).
TRUSTED_SUSTAINABILITY

Specifications

Antigen NQO1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NQO1
Gene Accession No. P15559
Gene Alias AV001255; Azoreductase; DHQU; DIA4; Diaphorase (NADH/NADPH); diaphorase (NADH/NADPH) (cytochrome b-5 reductase); Diaphorase 4; diaphorase 4 (NADH/NADPH); diaphorase-4; dioxin-inducible 1; DTD; DT-diaphorase; menadione reductase; NAD(P)H dehydrogenase (quinone); NAD(P)H dehydrogenase [quinone] 1; NAD(P)H dehydrogenase, quinone 1; NAD(P)H menadione oxidoreductase 1, dioxin inducible; NAD(P)H quinone dehydrogenase 1; NAD(P)H: quinone oxidoreductase 1; NAD(P)H:menadione oxidoreductase; NAD(P)H:menadione oxidoreductase 1; NAD(P)H:Quinone acceptor oxidoreductase type 1; NAD(P)H:quinone oxidoreductase 1; NAD(P)H:quinone oxireductase; NADPH-d; nicotinamide adenine dinucleotide phosphate diaphorase; Nmo1; Nmo-1; Nmor1; NMORI; NQ01; NQO1; Ox1; Ox-1; phylloquinone reductase; QR1; quinone reductase 1
Gene Symbols NQO1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NQO1. Recombinant protein control fragment (Product #RP-88713).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1728
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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