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Invitrogen™ NQO1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA585383
Description
Keep as concentrated solution. Predicted reactivity: Mouse (85%), Rat (83%), Pig (92%), Rhesus Monkey (98%), Bovine (92%), Guinea pig (86%). Positive Control: HeLa, HepG2, mouse heart. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Altered expression of the protein has been seen in many tumors and is also associated with Alzheimer's disease (AD).
Specifications
NQO1 | |
Polyclonal | |
Unconjugated | |
NQO1 | |
AV001255; Azoreductase; DHQU; DIA4; Diaphorase (NADH/NADPH); diaphorase (NADH/NADPH) (cytochrome b-5 reductase); Diaphorase 4; diaphorase 4 (NADH/NADPH); diaphorase-4; dioxin-inducible 1; DTD; DT-diaphorase; menadione reductase; NAD(P)H dehydrogenase (quinone); NAD(P)H dehydrogenase [quinone] 1; NAD(P)H dehydrogenase, quinone 1; NAD(P)H menadione oxidoreductase 1, dioxin inducible; NAD(P)H quinone dehydrogenase 1; NAD(P)H: quinone oxidoreductase 1; NAD(P)H:menadione oxidoreductase; NAD(P)H:menadione oxidoreductase 1; NAD(P)H:Quinone acceptor oxidoreductase type 1; NAD(P)H:quinone oxidoreductase 1; NAD(P)H:quinone oxireductase; NADPH-d; nicotinamide adenine dinucleotide phosphate diaphorase; Nmo1; Nmo-1; Nmor1; NMORI; NQ01; NQO1; Ox1; Ox-1; phylloquinone reductase; QR1; quinone reductase 1 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
1728, 18104 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
0.87 mg/mL | |
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
P15559, Q64669 | |
NQO1 | |
Recombinant protein encompassing a sequence within the center region of human NQO1. | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
Safety and Handling
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