Invitrogen™ NR0B1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595912

Catalog No. PIPA595912

Description

Immunogen sequence: MAGENHQWQG SILYNMLMSA KQTRAAPEAP ETRLVDQCWG CSCGDEPGVG REGLLGGRNV ALLYRCCFCG KDHPRQGSIL YSMLTSAKQT YAAPKAPEAT LGPCWGCSCG SDPGVGRAGL PGGRPVALLY RCCFCGEDHP RQGSILYSLL TSSKQTHVAP AAPEARPGGA WWDRSYFAQR PGGKEALPGG RATALLYRCC FCGEDHPQQG STLYCVPTST NQAQAAPEER PRAPWWDTSS GALRPVALKS PQVVCEAASA; Positive Samples: HeLa, Jurkat, MCF7, HepG2, Raji, Mouse spleen; Cellular Location: Cytoplasm, Nucleus.

This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.

Specifications

• Antigen: NR0B1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NR0B1
• Gene Alias: adrenal hypoplasia, congenital homolog; AHC; Ahch; AHX; DAX; DAX 1; Dax1; DAX-1; DSS; DSS-AHC critical region on the X chromosome protein 1; GTD; HHG; Nr0b1; NROB1; nuclear hormone receptor; nuclear receptor DAX-1; Nuclear receptor subfamily 0 group B member 1; nuclear receptor subfamily 0, group B, member 1; orphan nuclear receptor DAX-1; R0B1; SRXY2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11614, 190
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 2.96 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: P51843, Q61066
• Gene Symbols: NR0B1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human NR0B1 (NP_0004662).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov