NR1H2 Mouse anti-Human, Porcine, Clone: 1E12B10, Proteintech

Catalog No.	Quantity
50-173-6432	150 μL

Catalog No. 50-173-6432 Supplier Proteintech Group Inc Supplier No. 603451IG150UL

Description

Mouse Monoclonal Antibody

LXR-B belongs to the Liver X Receptor family that encodes highly homologous transcription factors. Like the highly homologous LXR-A, LXR-B forms heterodimers with the retinoic acid receptor RXRalpha, which function as sensors for cellular oxysterols which when activated, increase the expression of genes that control sterol and fatty acid metabolism and homeostasis. Recent experiments have indicated that the LXRs can also modulate both innate and adaptive immune responses. Other studies suggest that genetic variability at the LXR-B gene locus may be a risk factor for Alzheimer′s disease. One hypothesis postulates that LXR may be upstream of ApoE and potentiates the risk associated effects of the epsilon3 allele.

Specifications

• Antigen: NR1H2
• Applications: Western Blot
• Classification: Monoclonal
• Clone: 1E12B10
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: NR1H2
• Gene Accession No.: P55055
• Gene Alias: Liver X receptor beta, LXR b, LXRB, NER, NER I, NR1H2, Nuclear receptor NER, Oxysterols receptor LXR beta, RIP15, UNR
• Gene Symbols: NR1H2
• Host Species: Mouse
• Immunogen: NR1H2 Fusion Protein Ag5635
• Purification Method: Protein G
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 100525290, 7376
• Target Species: Human, Pig
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1