NR1H3 Monoclonal Antibody (OTI1F5), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA805049

Catalog No. 50-168-0530

Description

The liver X receptors, LXRA and LXRB (NR1H2), form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements.

Specifications

• Antigen: NR1H3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q13133
• Gene Symbols: NR1H3
• Immunogen: Human recombit protein fragment corresponding to amino acids 69-329 of human NR1H3 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot
• Clone: OTI1F5
• Conjugate: Unconjugated
• Gene: NR1H3
• Gene Alias: LXR-a, LXRA, RLD-1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10062
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid