NR2E3 Monoclonal Antibody (OTI10C4), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA806275

Catalog No. 50-168-1047

Description

NR2E3, a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It has been shown to have a role in determining photoreceptor phenotype during human retinogenesis. In RD7 mice, a deletion in NR2E3 results in hereditary retinal dysplasia and degeneration. A homozygous missense mutation in NR2E3 has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte. Two alternatively spliced isoforms have been documented. NR2E3 is expressed in the retina. ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.

Specifications

• Antigen: NR2E3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q9Y5X4
• Gene Symbols: NR2E3
• Immunogen: Full length human recombit protein of human NR2E3 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI10C4
• Conjugate: Unconjugated
• Gene: NR2E3
• Gene Alias: ESCS, PNR, RNR, RP37, rd7
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10002
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid