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NR2E3 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981483
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100 μL
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50-198-1483 100 μL
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Catalog No. 50-198-1483 Supplier Bioss Supplier No. BS11572R
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Rabbit Polyclonal Antibody

NR2E3, a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It has been shown to have a role in determining photoreceptor phenotype during human retinogenesis. In RD7 mice, a deletion in NR2E3 results in hereditary retinal dysplasia and degeneration. A homozygous missense mutation in NR2E3 has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte. Two alternatively spliced isoforms have been documented. NR2E3 is expressed in the retina. ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.

Specifications

Antigen NR2E3
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene NR2E3
Gene Accession No. Q9Y5X4
Gene Alias A930035N01Rik; ESCS; MGC138414; MGC138416; NR2E3; Nuclear receptor subfamily 2 group E member 3; nuclear receptor subfamily 2, group E, member 3; Photoreceptor-specific nuclear receptor; Pnr; rd7; retinal degeneration 7; Retina-specific nuclear receptor; Rnr; RP11-295F4.5; RP37; taR-5
Gene Symbols NR2E3
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human NR2E3.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10002
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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