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Invitrogen™ NR3C2 Polyclonal Antibody
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Catalog No. PIPA584969
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100 μL
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PIPA584969 100 μL
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Catalog No. PIPA584969 Supplier Invitrogen™ Supplier No. PA584969
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PSSAIVGVNS GGQSFHYRIG AQGTISLSRS ARDQSFQHLS SFPPVNTLVE SWKSHGDLSS RRSDGYPVLE YIPENVSSST L Highest antigen sequence indentity to the following orthologs: Mouse - 95%, Rat - 98%.

Steroid receptors are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Mineralocorticoids are a family of steroids, secreted by the adrenal cortex, necessary for the regulation of a number of metabolic processes including electrolyte regulation. These compounds exert their effect through their interaction with the mineralocorticoid receptor (MR) and that complex's subsequent association with DNA. Given the function of mineralocorticoids, it is not surprising to find that the kidney is a primary target organ for mineralocorticoids and that this organ has been shown to contain MR. The corresponding gene for the mineralocorticoid receptor is NR3C2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NR3C2
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NR3C2
Gene Accession No. P08235
Gene Alias aldosterone receptor; MCR; Mineralocorticoid receptor; Mineralocorticoid receptor (aldosterone receptor); mineralocorticoid receptor 1; mineralocorticoid receptor 2; mineralocorticoid receptor delta; Mlr; MR; NR3C2; NR3C2VIT; nuclear hormone receptor; nuclear receptor subfamily 3 group C member 2; nuclear receptor subfamily 3, group C, member 2; nuclear receptor subfamily 3, group C, member 2 variant 3
Gene Symbols NR3C2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NR3C2. Recombinant protein control fragment (Product #RP-108024).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4306
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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