Invitrogen™ NR5A2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589359

Catalog No. PIPA589359

Description

Immunogen sequence: SIPHLILELL KCEPDEPQVQ AKIMAYLQQE QANRSKHEKL STFGLMCKMA DQTLFSIVEW ARSSIFFREL KVDDQMKLLQ NCWSELLILD HIYRQVVHGK EGSIFLVTGQ QVDYSIIASQ AGATLNNLMS HAQELVAKLR SLQFDQREFV CLKFLVLFSL DVKNLENFQL VEGVQEQVNA ALLDYTMCNY PQQTEKFGQL LLRLPEIRAI SMQAEEYLYY KHLNGDVPYN NLLIEMLHAK RA Positive Samples: Mouse liver; Cellular Location: Nucleus.

Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.

Specifications

• Antigen: NR5A2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Nr5a2
• Gene Alias: Alpha-1-fetoprotein transcription factor; AU020803; B1-binding factor; b1-binding factor, hepatocyte transcription factor which activates enhancer II of hepatitis B virus; B1F; B1F2; CPF; CYP7A promoter-binding factor; D1Ertd308e; fetoprotein transcription factor; fetoprotein-alpha 1 (AFP) transcription factor; Ftf; FTF/LRH-1; FTZ F1; FTZ F1beta; FTZ-F1; FTZ-F1 beta; FTZ-F1 beta2 protein; FTZ-F1beta; hB1F; hB1F 2; hB1F-2; Hepatocytic transcription factor; hepatocytic transcription factor hB1F-3; I79_021747; live; liver nuclear receptor homolog-1 variant 2; liver receptor homolog 1; liver receptor homolog-1; Lrh1; LRH-1; Nr5a2; Nuclear receptor subfamily 5 group A member 2; nuclear receptor subfamily 5, group A, member 2; OR2.0; orphan nuclear receptor; SF-2; steroidogenic factor 2; UF2-H3B
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2494, 26424, 60349
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 2.68 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: O00482, P45448, Q9QWM1
• Gene Symbols: Nr5a2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 300-541 of human NR5A2 (NP_9955821).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG