Invitrogen™ NR5A2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110041

Catalog No. PIPA5110041

Description

Immunogen sequence: SIPHLILELL KCEPDEPQVQ AKIMAYLQQE QANRSKHEKL STFGLMCKMA DQTLFSIVEW ARSSIFFREL KVDDQMKLLQ NCWSELLILD HIYRQVVHGK EGSIFLVTGQ QVDYSIIASQ AGATLNNLMS HAQELVAKLR SLQFDQREFV CLKFLVLFSL DVKNLENFQL VEGVQEQVNA ALLDYTMCNY PQQTEKFGQL LLRLPEIRAI SMQAEEYLYY KHLNGDVPYN NLLIEMLHAK RA.

Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.

Specifications

• Antigen: NR5A2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Nr5a2
• Gene Alias: Alpha-1-fetoprotein transcription factor; AU020803; B1-binding factor; b1-binding factor, hepatocyte transcription factor which activates enhancer II of hepatitis B virus; B1F; B1F2; CPF; CYP7A promoter-binding factor; D1Ertd308e; fetoprotein transcription factor; fetoprotein-alpha 1 (AFP) transcription factor; Ftf; FTF/LRH-1; FTZ F1; FTZ F1beta; FTZ-F1; FTZ-F1 beta; FTZ-F1 beta2 protein; FTZ-F1beta; hB1F; hB1F 2; hB1F-2; Hepatocytic transcription factor; hepatocytic transcription factor hB1F-3; I79_021747; live; liver nuclear receptor homolog-1 variant 2; liver receptor homolog 1; liver receptor homolog-1; Lrh1; LRH-1; Nr5a2; Nuclear receptor subfamily 5 group A member 2; nuclear receptor subfamily 5, group A, member 2; OR2.0; orphan nuclear receptor; SF-2; steroidogenic factor 2; UF2-H3B
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2494, 26424, 60349
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.81 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O00482, P45448, Q9QWM1
• Gene Symbols: Nr5a2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 300-541 of human NR5A2 (NP_9955821).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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