Invitrogen™ NRCAM Monoclonal Antibody (7D8C5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531810

Catalog No. PIMA531810

Description

MA5-31810 has been tested in indirect ELISA.

Neuron-glia-related cell adhesion molecule (NRCAM) is a gene located on chromosome 7q31.1, encoding a protein that belongs to the immunoglobulin superfamily of cell adhesion molecules. NRCAM is expressed in the nervous system and plays a vital role in the development and maintenance of neural connections. This adhesion molecule facilitates neuron-neuron and neuron-glia interactions, impacting processes such as axon guidance, synapse formation, and cell signaling, which are crucial for neural development and plasticity. NRCAM is involved in the modulation of signal transduction pathways that influence neuronal growth and repair, contributing to the stabilization of synaptic structures. Alterations in NRCAM expression or function have been linked to neurodevelopmental disorders, including autism spectrum disorders, and certain psychiatric conditions, reflecting its importance in maintaining neural circuit integrity. Research into NRCAM continues to explore its therapeutic potential in neurobiology and its implications in neurological and psychiatric disorders.

Specifications

• Antigen: NRCAM
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: Q92823
• Gene Symbols: NRCAM
• Immunogen: Purified recombinant fragment of human NRCAM (AA: 1192-1255) expressed in E. coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: 7D8C5
• Conjugate: Unconjugated
• Gene: NRCAM
• Gene Alias: ankyrin-binding cell adhesion molecule NrCAM; Bravo; C030017F07Rik; C130076O07Rik; hBravo; KIAA0343; mBravo; MGC138845; MGC138846; mKIAA0343; neuronal cell adhesion molecule; Neuronal surface protein Bravo; neuron-glia-CAM-related cell adhesion molecule; ng-CAM-related; NgCAM-related cell adhesion molecule; Nr CAM; Nrcam; nr-CAM; rBravo
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 4897
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid