Invitrogen™ NRF1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527854

Catalog No. PIPA527854

Description

Recommended positive controls: 293T, 293T nuclear, A431, A431 nuclear, HeLa, HeLa nuclear, HepG2, HepG2 nuclear. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (94%), Xenopus laevis (94%), Chicken (99%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2)-like 1' which has an official symbol of NFE2L1.

Specifications

• Antigen: NRF1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NRF1
• Gene Alias: Alpha palindromic-binding protein; alpha-pal; C87038; D6Ertd415e; EWG; LOW QUALITY PROTEIN: nuclear respiratory factor 1; Nfe2l1_retired; Not really finished protein; nrf; Nrf1; NRF-1; nrf1 protein; nrl; nuclear respiratory factor 1; nuclear respiratory factor-1; SC:BZ3C13.1; SC:bZ3C13.2; transcription factor; ube2h
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18181, 312195, 4899
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1.32 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q16656, Q62792, Q9WU00
• Gene Symbols: NRF1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human NRF1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG