Invitrogen™ Nrf2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120048

Catalog No. PIPA5120048

Description

Immunogen sequence: SPHFLNAFED SFSSILSTED PNQLTVNSLN SDATVNTDFG DEFYSAFIAE PSISNSMPSP ATLSHSLSEL LNGPIDVSDL SLCKAFNQNH PESTAEFNDS DSGISLNTSP SVASPEHSVE SSSYGDTLLG LSDSEVEELD SAPGSVKQNG PKTPVHSS Positive test controls include: HeLa, NIH/3T3. The target is usually found in the following locations: Cytoplasm, Nucleus, cytosol.

Nfr1 (also designated TCF11), Nrf2 and Nfr3 are bZIP transcription factors that heterodimer with Maf proteins to bind MARE (Maf recognition elements) sequences. Nrf2 is widely expressed and is thought to translocate to the nucleus after treatment with xenobiotics and antioxidants, which stimulate its release from a repressor protein Keap1.

Specifications

• Antigen: Nrf2
• Classification: Polyclonal
• Concentration: 1.13 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: O54968, Q16236, Q60795
• Gene Symbols: NFE2L2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 243-400 of human NRF2 (NP_0061552).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 6W6R7
• Conjugate: Unconjugated
• Gene: NFE2L2
• Gene Alias: AI194320; E4TF1-60; E4TF1A; HEBP1; Nfe2l2; NF-E2-related factor 2; NFE2-related factor 2; NF-E2-related factor-2; NFT2; NRF2; NRF2A; nuclear factor (erythroid-derived 2)-like 2; nuclear factor erythroid 2-like 2; nuclear factor erythroid 2-related factor 2; nuclear factor erythroid-derived 2-like 2; nuclear factor, erythroid 2 like 2; nuclear factor, erythroid 2-like 2; nuclear factor, erythroid derived 2, like 2; Unknown (protein for IMAGE:7945830)
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18024, 4780, 83619
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid