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Invitrogen™ Nrf2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527882

Catalog No. PIPA527882


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Description

Description

Recommended positive controls: C8D30, 3xFlag-human NFE2L2-transfected 293T, MDA-MB-231 nuclear extract, MDA-MB-231 nuclear extract (30 μM tBHQ, 4hr), HepG2 (10 μM MG132 treatment for 15 hr). Predicted reactivity: Rhesus Monkey (99%), Bovine (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Nfr1 (also designated TCF11), Nrf2 and Nfr3 are bZIP transcription factors that heterodimer with Maf proteins to bind MARE (Maf recognition elements) sequences. Nrf2 is widely expressed and is thought to translocate to the nucleus after treatment with xenobiotics and antioxidants, which stimulate its release from a repressor protein Keap1.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Nrf2
Polyclonal
Unconjugated
NFE2L2
AI194320; E4TF1-60; E4TF1A; HEBP1; Nfe2l2; NF-E2-related factor 2; NFE2-related factor 2; NF-E2-related factor-2; NFT2; NRF2; NRF2A; nuclear factor (erythroid-derived 2)-like 2; nuclear factor erythroid 2-like 2; nuclear factor erythroid 2-related factor 2; nuclear factor erythroid-derived 2-like 2; nuclear factor, erythroid 2 like 2; nuclear factor, erythroid 2-like 2; nuclear factor, erythroid derived 2, like 2; Unknown (protein for IMAGE:7945830)
Rabbit
Antigen affinity chromatography
RUO
18024, 4780, 83619
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
ChIP Assay, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
0.26 mg/mL
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
O54968, Q16236, Q60795
NFE2L2
Recombinant fragment corresponding to a region within amino acids 108 and 413 of Human NRF2.
100 μL
Primary
Human, Mouse, Rat, Avian, Reptile, Zebrafish, Plant
Antibody
IgG
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