Invitrogen™ Nrf2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5119633

Catalog No. PIPA5119633

Description

Positive Control: Mouse liver tissue lysates, Hela, HepG2, Huvec, rat brain tissue, human lung tissue, mouse fallopian tubes tissue, human spleen tissue, human uterus tissue. Subcellular Location: Cytoplasm. Nucleus.

Nfr1 (also designated TCF11), Nrf2 and Nfr3 are bZIP transcription factors that heterodimer with Maf proteins to bind MARE (Maf recognition elements) sequences. Nrf2 is widely expressed and is thought to translocate to the nucleus after treatment with xenobiotics and antioxidants, which stimulate its release from a repressor protein Keap1.

Specifications

• Antigen: Nrf2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NFE2L2
• Gene Alias: AI194320; E4TF1-60; E4TF1A; HEBP1; Nfe2l2; NF-E2-related factor 2; NFE2-related factor 2; NF-E2-related factor-2; NFT2; NRF2; NRF2A; nuclear factor (erythroid-derived 2)-like 2; nuclear factor erythroid 2-like 2; nuclear factor erythroid 2-related factor 2; nuclear factor erythroid-derived 2-like 2; nuclear factor, erythroid 2 like 2; nuclear factor, erythroid 2-like 2; nuclear factor, erythroid derived 2, like 2; Unknown (protein for IMAGE:7945830)
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18024, 4780, 83619
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunocytochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: TBS with 0.5% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: O54968, Q16236, Q60795
• Gene Symbols: NFE2L2
• Immunogen: Synthetic peptide within N-terminal human Nrf2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov