NRGN Mouse anti-Human, Clone: OTI1A2, lyophilized, TrueMAB™

Catalog No.	Quantity
50-167-0825	100 μg

Catalog No. 50-167-0825 Supplier OriGene Supplier No. CF811753

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Neurogranin is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.

Specifications

• Antigen: NRGN
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI1A2
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: NRGN
• Gene Accession No.: Q92686
• Gene Alias: RC3, hng
• Gene Symbols: NRGN
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-78 of human NRGN produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4900
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1