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Invitrogen™ NRGN Polyclonal Antibody
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Catalog No. PIPA558281
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100 μL
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Catalog No. Quantity
PIPA558281 100 μL
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Catalog No. PIPA558281 Supplier Invitrogen™ Supplier No. PA558281
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MDCCTENACS KPDDDILDIP LDDPGAN Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

Neurogranin is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NRGN
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NRGN
Gene Accession No. Q92686
Gene Alias 0710001B06Rik; AI838505; B-50 immunoreactive C-kinase substrate; BICKS; calmodulin-binding protein; hng; NEUG(55-78); Neurogranin; neurogranin (protein kinase C substrate, RC3); ng; NG/RC3; NRGN; p17; postsynaptic spine 1; protein kinase C substrate; protein kinase C substrate 7.5 kDa protein; protein kinase C substrate, RC3; Pss1; R75334; RC3; similar to neurogranin
Gene Symbols NRGN
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NRGN. Recombinant protein control fragment (Product #RP-97413).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4900
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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