Invitrogen™ NRGN Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA576392

Catalog No. PIPA576392

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Neurogranin is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.

Specifications

• Antigen: NRGN
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NRGN
• Gene Alias: 0710001B06Rik; AI838505; B-50 immunoreactive C-kinase substrate; BICKS; calmodulin-binding protein; hng; NEUG(55-78); Neurogranin; neurogranin (protein kinase C substrate, RC3); ng; NG/RC3; NRGN; p17; postsynaptic spine 1; protein kinase C substrate; protein kinase C substrate 7.5 kDa protein; protein kinase C substrate, RC3; Pss1; R75334; RC3; similar to neurogranin
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4900, 64011, 64356
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P60761, Q04940, Q92686
• Gene Symbols: NRGN
• Immunogen: Recombinant protein of human NRGN.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG