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Invitrogen™ NRGN Polyclonal Antibody
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Catalog No. PIPA519209
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100 μg
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Catalog No. Quantity
PIPA519209 100 μg
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Catalog No. PIPA519209 Supplier Invitrogen™ Supplier No. PA519209
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Description

Goat Polyclonal Antibody

This antibody is predicted to react with bovine and canine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.

Neurogranin is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NRGN
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene NRGN
Gene Accession No. Q92686
Gene Alias 0710001B06Rik; AI838505; B-50 immunoreactive C-kinase substrate; BICKS; calmodulin-binding protein; hng; NEUG(55-78); Neurogranin; neurogranin (protein kinase C substrate, RC3); ng; NG/RC3; NRGN; p17; postsynaptic spine 1; protein kinase C substrate; protein kinase C substrate 7.5 kDa protein; protein kinase C substrate, RC3; Pss1; R75334; RC3; similar to neurogranin
Gene Symbols NRGN
Host Species Goat
Immunogen Synthetic peptide sequence (KIKSGERGRKG) corresponding to the internal amino acids of NRGN (aa 45-56).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4900
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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